Volume 7, Issue 64  |  August 12, 2022

Hoag now offers the most comprehensive Aortic Disease Center in Southern California

Hoag’s Jeffrey M. Carlton Heart & Vascular Institute recently expanded its ability to manage and treat complex aortic pathology with the launch of the Hoag Clinic for Marfan Syndrome and Related Conditions. Hoag is one of only two hospitals in California to offer these services to the specialized care provided at the Elaine & Robert Matranga Aortic Center, recently named following a generous gift by the couple.

Aortic disease, especially in patients with connective tissue conditions, can lead to arterial rupture or dissection, which kills more than 15,000 people every year. Home to some of the most skilled surgeons, cardiologists and physician specialists, Hoag’s comprehensive approach spans from active surveillance to leading-edge treatments such as valve-sparing aortic root replacement, descending thoracic aortic stent grafts or hybrid endovascular approaches. In addition, Hoag offers 24/7 emergency care services for acute aortic emergencies.

Hoag’s newest team member, David Liang, M.D., Ph.D., leads the Marfan Syndrome and Related Conditions clinic as the program director. Dr. Liang is a specialist in the rare condition Marfan syndrome, as well as other related connective tissue conditions. He is internationally recognized as an exceptional physician and dedicated patient advocate, as well as a member of The Marfan Foundation’s Professional Advisory Board.

Hoag now offers aortic team

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(L-R) Back row: Carey O’Bryan, M.D.; Anthony Caffarelli, M.D., director, Hoag Cardiovascular Surgery; David Liang, M.D. Front row: Megan Boeglin, RN; Christian D’Angelo, patient with Marfan Syndrome; and Rita Weise, nurse practitioner

“Patients with Marfan syndrome or a related condition not only need to be closely monitored for aortic disease but also require specialty care in many other areas including orthopedics, physical therapy, pulmonology, pain management, and perinatology,” explained Dr. Liang.

Hoag’s network of compassionate and highly qualified physicians and nurses offers a multidisciplinary team to provide comprehensive care for rare or complex conditions.

“If you or a loved one is living with a connective tissue condition, you know that finding the care you need can be tough and coordinating between specialists can be tougher. We have created the Hoag Clinic for Marfan Syndrome & Related Conditions to help bring top-level doctors who understand your medical need to Southern California. Simply calling or emailing the center directly, you will be navigated to the right team member,” said cardiothoracic surgeon Anthony Caffarelli, M.D., director of Hoag Cardiac Surgery, Elaine & Robert Matranga Aortic Center and the Newkirk Family Endowed Chair in Aortic Care.

“My role is to closely monitor and help patients manage their conditions. Despite active surveillance, many of our patients need to have aortic surgery. Partnering with a great cardiac program and surgical team will be a great service for patients in Southern California and the surrounding areas,” said Dr. Liang.

Hoag’s commitment to combining compassion with state-of-the-art facilities and superior physician talent has earned the Jeffrey M. Carlton Heart & Vascular Institute at Hoag a leading national reputation. Recently, the Society for Thoracic Surgeons rated Hoag’s Cardiac Surgery Program 3 out of 3 stars for both coronary artery bypass grafting and aortic surgery – an achievement reached by only the top 1.8 percent of programs in the country.

“This partnership speaks volumes about the commitment we have made to our community to expand what we offer to include highly specialized doctors who can provide high-quality care for even the rarest diseases. We are very excited to have Dr. Liang here at Hoag,” said Dr. Caffarelli.

Hoag is also collaborating with The Marfan Foundation to connect with leading researchers and community members in combating these conditions to support patients and families. On Saturday, Feb. 29, Hoag will be the presenting sponsor of The Foundation’s Southern California Walk for Victory. The walk brings together connective tissue condition patients from all over Southern California, allowing them to connect and further build a community of support. For more details, visit

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